New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

Findings from a preclinical study demonstrate that Omomyc—the only direct MYC inhibitor to have successfully completed a ...

The composition and sequence of 3 billion bases of DNA serve as a major determinant of our individual physiology. Unfortunately, our DNA is constantly being challenged by agents that arise from either ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres—the protective ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...