New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

The composition and sequence of 3 billion bases of DNA serve as a major determinant of our individual physiology. Unfortunately, our DNA is constantly being challenged by agents that arise from either ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery ...

Findings from a preclinical study demonstrate that Omomyc—the only direct MYC inhibitor to have successfully completed a ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres—the protective ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...