When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...

Failure to repair DNA damage can result in DNA lesions and mutations that are a driving factors in cancer development. Recent work has identified a function for DNA damage repair mechanism beyond ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

Many people lather up with sunscreen or cover up with hats to protect themselves from the sun’s harmful rays. These added layers help to shield the skin from ultraviolet (UV) light, which damages DNA ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of medications that fix tissue damage caused by heart attack, inflammatory ...

New research shows that CTE may stem from DNA damage and inflammation set in motion by blows to the head.