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New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
Tuberculosis (TB) is one of the oldest and deadliest infectious diseases we know. It commonly impacts the lungs, but can also ...
The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...
Modern DNA/RNA sequencing technologies, known generally as “next-generation sequencing” (NGS) technologies, allow us to decode nucleic acid sequences in high throughput; therefore, much faster and ...
The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell division ...
Get your news from a source that’s not owned and controlled by oligarchs. Sign up for the free Mother Jones Daily. In November 2016, virologist David Evans traveled to Geneva for a meeting of a World ...
On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a ‘vomit comet’ flight, where the plane repeatedly climbs to 8km in a steep ...
The development of DNA-/RNA-based drugs, like COVID-19 vaccines, is exploding. Current methods are costly, but researchers are finding effective and inexpensive method for producing stable, modified ...
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