Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...

Researchers discovered that stiff DNA segments inside nucleosomes physically block chromatin remodeling. The remodeling ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other’s binding to DNA in fission yeast. They found that ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...