When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Researchers have used a new human reference genome, which includes many duplicated and repeat sequences left out of the original human genome draft, to identify genes that make the human brain ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, ...

NIH funding has allowed scientists to see the DNA blueprints of human life—completely. In 2022, the Telomere-to-Telomere Consortium, a group of NIH-funded scientists from research institutions around ...

The Human Genome Project was among the most ambitious scientific efforts in modern history, with the aim of deciphering the chemical makeup of the entire human genetic code. The sequence of some 3 ...

Around 98.5% of human DNA is non-coding, meaning it doesn’t get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for ...

The chromosome associated with male development, which is the last mysterious piece of the human genome, has been fully sequenced by a team of more than 100 researchers around the world, including ...

Today, genomics is saving countless lives and even entire species, thanks in large part to a commitment to collaborative and open science that the Human Genome Project helped promote. Twenty-five ...

The human genome is made up of 23 pairs of chromosomes, the biological blueprints that make humans … well, human. But it turns out that some of our DNA — about 8% — are the remnants of ancient viruses ...

A team of UK-based researchers is going where no scientist has dared to go—writing artificial human DNA from scratch. They’re hoping the project will answer fundamental questions about the human ...