The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

New live-cell DNA damage sensor lets scientists watch repair unfold in real time, potentially opening doors for cancer and aging research.

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

RNA, widely known from the COVID-19 vaccine, is not actually a "therapeutic agent," but a technology that delivers the ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Targeting highly aggressive ductal prostate tumours with poly ADP ribose polymerase inhibitor (PARPi) and androgen receptor signaling inhibitor (ARSi) combination therapy. This is an ASCO Meeting ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden.

Tumor Transcriptome Reveals the Predictive and Prognostic Impact of Lysosomal Protease Inhibitors in Non–Small-Cell Lung Cancer A retrospective cohort of 473 patients treated for endometrial carcinoma ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...