Evo’s success wasn’t limited to proteins. When they tested a different toxin that had an RNA-based inhibitor, the system ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Researchers have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Recent research has delved deep into the manifold ways in which diet can affect gut health throughout a person's life. Here ...

The microbe Pyrodictium abyssi is an archaeon—a member of what's known as the third domain of life—and an extremophile. It ...

This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...

Microplastics gather drug resistant bacteria as they move through water, allowing microbes to spread from polluted sites into ...

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, ...

Northwestern Medicine scientists have identified previously unknown genetic mechanisms that promote antimicrobial resistance in gonorrhea, findings that may inform the development of more effective ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Detectives often find important clues by digging through rubbish. That approach paid off tremendously for systems biologist Yifat Merbl. When she and her team investigated cellular recycling centres ...

"Adapt or perish, now as ever, is nature's inexorable imperative," wrote H. G. Wells. This principle—that survival requires ...