Sequence analysis is a cornerstone of modern bioinformatics, encompassing the computational exploration of biological sequences—be they DNA, RNA or proteins—to reveal insights into structure, function ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

Single-cell sequencing provides unprecedented detail into cell-to-cell variability, uncovering key biological mechanisms in ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

When off-target regions are affected by genome editing, unexpected changes in the mRNA quantity and sequence can emerge. The DANGER analysis is designed to analyze the effects from RNA-seq data at the ...

The Advances in Genome Biology and Technology (AGBT) meeting celebrated its 25 th anniversary in sunny Marco Island, Florida, with the customary mix of big name speakers addressing researchers and ...