Mitotic stopwatch pathway shows how cancer loses its sense of time to avoid stress responses

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example, DNA damage ...

CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study

A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

Reversing treatment resistance in prostate cancer: Study solves longstanding puzzle in tumor biology

Scientists at the Herbert Irving Comprehensive Cancer Center (HICCC) have discovered a key mechanism that makes prostate cancer cells resistant to the latest drugs used to treat them. Their findings, ...

Hidden metabolic weakness in blood cancers revealed by new mapping tool

Scientists from Duke-NUS Medical School and their international collaborators have developed a new computational tool that ...
Scientific American

Why Locking on to Cells Could Turbocharge Cancer Immunotherapy

Bispecific antibodies bring multiple tumor-cell-killing mechanisms into play simultaneously. When a T cell is activated and ...
Study Finds

Childhood Virus Linked To Bladder Cancer Decades Later

A virus carried by 95% of adults from childhood may trigger bladder cancer decades later by damaging cells during immune ...

Scientists Solve Pancreatic Cancer Mystery: Key Driver of Unusually Deadly Spread Identified

A newly identified cancer pathway may finally reveal how to stop pancreatic tumors before they spread. A Cornell-led research ...