After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

Macrophages can forge synaptic-like links with muscle fibers, sending rapid calcium signals that accelerate regeneration. The finding reveals a fast, unexpected repair pathway with major therapeutic ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

Major Finding: The REPAIRome reveals how each human gene influences the outcomes of double-strand break repair. Approach: Genome-wide knockouts paired with insertion and deletion profiling establish a ...